Health Encyclopedia

Compazine overdose

Definition

Compazine is a drug used to treat severe nausea and vomiting. Compazine overdose occurs when someone accidentally or intentionally takes more than the normal or recommended amount of this medication.

This is for information only and not for use in the treatment or management of an actual poison exposure. If you have an exposure, you should call your local emergency number (such as 911) or the National Poison Control Center at 1-800-222-1222.

Poisonous Ingredient

Prochlorperazine

Where Found

Buccastem
Compazine
Spansule
Stemetil

Symptoms

Bladder and kidneys
- Inability to completely empty the bladder
Eyes, ears, nose, mouth, and throat
- Blurred vision
- Drooling
- Dry mouth
- Nasal congestion
- Yellow eyes
Gastrointestinal system
- Constipation
- Loss of appetite
- Nausea
- Swallowing difficulties
Heart and blood
- Convulsions
- Low blood pressure (severe)
- Rapid heartbeat
Muscles and joints
- Muscle spasms
- Stiff muscles in neck, face, or back
Nervous system
- Coma
- Disorientation
- Drowsiness
- Fever
- Hypothermia (body temperature is lower than normal)
- Tremor
- Uncoordinated movement
- Weakness
Reproductive system
- Changes in menstrual patterns
Skin
- Rash
- Yellow skin

Before Calling Emergency

Determine the following information:

Patient's age, weight, and condition
The name of the product (ingredients and strengths, if known)
When it was swallowed
The amount swallowed
If the medication was prescribed for the patient

Poison Control, or a local emergency number

The National Poison Control Center (1-800-222-1222) can be called from anywhere in the United States. This national hotline number will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

See: Poison control center - emergency number

What to expect at the emergency room

The health care provider will measure and monitor the patient's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated as appropriate. The patient may receive:

Activated charcoal
Laxative
Fluids
Tube through the nose into the stomach to wash out the stomach (gastric lavage)

Expectations (prognosis)

Compazine is relatively safe. Most likely it will only cause drowsiness and some side effects such as temporary uncontrolled movements of your lips, eyes, and head.

However, rarely it can cause some more serious symptoms. Full recovery is likely in all but the most serious and rare cases.

Review Date:2/3/2009
Reviewed By:A.D.A.M. Editorial Team: David Zieve, MD, MHA, Greg Juhn, MTPW, David R. Eltz. Previously reviewed by Eric Perez, MD, Department of Emergency Medicine, St. Luke's-Roosevelt Hospital Center, New York, NY. Review provided by VeriMed Healthcare Network (1/23/2008).

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